Frank's Sign: Diagonal Earlobe Crease

*Corresponding Author:
Tom Edward Mallinson
Department of Anaesthesia
Royal Derby Hospital, Derbyshire
DE22 3NE, United Kingdom
Tel: 07495 238698
e-mail: Tom.Mallinson@NHS.net

Abstract

Given Clinical Image shows a pronounced diagonal earlobe crease (Frank’s sign) first described in 1973 [1]. Frank’s sign is strongly predictive of coronary artery disease but lacks enough specificity and sensitivity to make it pathognomonic. Frank’s Sign should be looked for as an objective marker of older age, in the same way as corneal arcus, xanthelasmata and greying hair.

Given Clinical Image shows a pronounced diagonal earlobe crease (Frank’s sign) first described in 1973 [1]. Frank’s sign is strongly predictive of coronary artery disease but lacks enough specificity and sensitivity to make it pathognomonic. Frank’s Sign should be looked for as an objective marker of older age, in the same way as corneal arcus, xanthelasmata and greying hair (Figure 1).

ijocs-Diagonal-Crease

Figure 1: Pronounced Diagonal Earlobe Crease (Frank’s Sign).

References