Abstract

Drugs: Behavioural effects

Author(s): Divya Prakash Ojha

The way your body and mind work is affected by drugs, and they can alter how you feel, think, and act. Drug use is a personal choice, with many motivations and methods. Animal behavioural models of psychiatric diseases cannot accurately replicate human psychopathology, but they can be used to assess the behavioural changes brought on by drugs and to make hypotheses regarding the functioning of the CNS and its participation in psychiatric disorders. The three key characteristics of drugs that support, guide, and control drug-seeking behaviour are their positively reinforcing, discriminative, and unpleasant stimulus features. Each process can be examined in terms of underlying neurological and behavioural mechanisms that interact and complement one another. The elicitation and maintenance of drug-seeking behaviour also depend heavily on environmental stimuli that have been trained to mimic the effects of the substances. Both the behavioural and neurological systems are susceptible to modifying elements like social, environmental, and genetic influences, as well as the person's prior behavioural and pharmaceutical experiences. Numerous animal models have been employed to investigate the link between social behaviour and drug misuse. Here, the discussion was done to know how various drugs of abuse affect the three most often used animal social behaviour models: the resident-intruder paradigm, the social play test, and the social interaction test.

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