Abstract

Medication Resistant Tuberculosis

Author(s): Katie William, Richard William and Tabitha Wilson

Medication-resistant tuberculosis is a significant public health threat that jeopardises the significant progress made in tuberculosis awareness and prevention in recent decades. Multidrug-resistant tuberculosis is caused by bacteria that are resistant to even the most powerful anti-tuberculosis drugs (isoniazid and rifampicin). Tuberculosis germs resistant to antibiotics used in treatment are widespread and can be found across entire countries. Medication resistance is defined as a pattern of inadequate treatment, and once tuberculosis organisms develop resistance, they can spread from person to person in the same way that medication-sensitive tuberculosis does. Multidrug-resistant tuberculosis sequences can arise through infection with previously medication-resistant organisms or as a patient's therapy progresses. Rifampicin-resistant tuberculosis is caused by bacteria that are resistant to rifampicin, which is one of the most widely used anti-tuberculosis drugs. Multidrug-resistant tuberculosis treatment was required for these patients. Multidrug-resistant tuberculosis is a type of tuberculosis produced by organisms that are resistant to isoniazid and rifampicin, as well as every fluoroquinolone and any of the second-line anti-tuberculosis injectable medicines (amikacin, kanamycin or capreomycin). When second-line drugs are taken poorly or incorrectly maintained, extended medication-resistant TB can develop and become ineffective.